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3DT Holdings, home

Five companies, each proven
in this building.

An incubator that owns an operating room does not have to take a founder's word for whether a device works. Nothing leaves 3DT as a company until it has survived a large-animal study downstairs.

Operating companies
05
Founded
2007
Model
Invent · prove · spin out
Macro of a guidewire distal tip: helical coil, atraumatic tip and ring electrodes
Plate 01
01Coronary and peripheral intervention

Intelligent Delivery Systems

Intelligent Delivery Systems, Inc.

Guidewires that measure.

Conductance moved out of the catheter and into the wire itself. The 35 Wire is a 0.035-inch guidewire that crosses a lesion, serves as the rail for everything delivered after it, and reports cross-sectional area from inside the artery, so the operator sizes the balloon and the stent from the wire already in place. A 0.014-inch coronary version is in development.

Lead program

The 35 Wire

Cross-section of intestinal mucosa with villi and epithelial nuclei
Plate 02
02Metabolic and bariatric

GRest

GRest, Inc.

Bariatric outcomes without the amputation.

Sleeve gastrectomy works and cannot be undone. GRest is developing a laparoscopic reversible gastric restrictive device expected to deliver comparable weight loss while staying reversible and leaving the anatomy intact, which matters most to the patients least willing to accept a permanent change. It is preclinical.

Lead program

RGR device

Fluorescent tracer perfusing a branching microvascular capillary bed
Plate 03
03Circulatory support

Retroperfusion

Retroperfusion, Inc.

Flow, running backward.

Minimally invasive circulatory support catheters for ischemic heart disease and critical limb ischemia. The same retrograde principle serves two clocks: acute, as a bridge through an infarct or an intervention, and chronic, for limbs with no arterial option left.

Lead program

Retrograde perfusion catheters

Cardiac muscle at high magnification with sarcomere striations and packed mitochondria
Plate 04
04Cardiac delivery

Pericardial Access

Pericardial Access

A door in the heart wall.

The pericardial space is the natural place to deliver gene therapy, cells and leads, and the hardest place to reach safely. The platform crosses outward from inside the right atrium rather than inward from the chest, turning a blind subxiphoid needle stick into a catheter procedure.

Lead program

Trans-atrial platform

A single spherical cardiac organoid in dark-field suspension
Plate 05
05Gastroenterology

GI Bionics

GI Bionics LLC

Fecobionics.

Constipation and fecal incontinence are diagnosed today with tests that bear little resemblance to defecation. Fecobionics is a wireless simulated stool that records pressure, bending, orientation and geometry through an actual event, and returns physiology instead of a proxy. The Fecobionics Anorectal System was cleared by the FDA in February 2025, the first clearance to come out of the portfolio.

Lead program

Fecobionics · FDA cleared 2025

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